0.22 μm hydrophilic PTFE membrane filter bubble points are above or equal 0.1MPa and 0.06MPa respectively, diameters ranging from 13mm, 25mm, 47mm to 90mm, 142mm, 293mm. Hydrophilic PTFE membrane pore size is 0.22μm, 0.45μm and chemical compatibilities are superior to aqueous, organic solvents and mixed solvents.