For example, syringe filters containing 0.45 μm are typically used for HPLC sample preparation and 0.2 μm is used for UHPLC. In life science applications 0.1 and 0.2 µm pore sizes provide sterilization of buffers, culture media, and additives. Larger 0.45, 0.8, 1.2 and 5 µm membrane pore sizes can be used for prefiltration and/or clarification.